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Boswellic acids have long been considered the main bioactive components of Boswellia serrata, and many studies in vitro and in animals have confirmed their bioactivities. In particular, recent mechanistic studies have validated the capacity of the β-boswellic acids group to modulate inflammatory response, but preliminary pharmacokinetic studies in animals and humans have highlighted their poor oral absorption. To overcome this problem, Indena has formulated a purified mixture of boswellic acids from Boswellia serrata with lecithin, taking advantage of its proprietary Phytosome technology platform to optimize their absorption.
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