Via Ortles 12




flavors and aromas; nutraceutical and functional food ingredients


Indena is the leading company dedicated to the identification, development and production of high quality active principles for the pharmaceutical and health food industries. In particular, Indena offers for the nutritional field botanical extracts from edible plants, with a full phytochemical characterization, safe and supported by advanced human studies. Backed up by almost a century of botanical experience, the Italian privately owned company invests a significant amount of its annual turnover in research, making this activity the key to its success.

Phyto-chemical research is carried out in Indena's own Research Center in Settala, Italy. Indena also co-operates with the world's most prestige universities and private research institutes in the biological assessment of the safety and effectiveness of its products up to clinical phase I/II.

A key strategic research objective is the development of new active principles for pharmaceutical applications. This also forms an indispensable base for the health-food and personal care industries.

The pharmaceutical side of the company is focused mainly on anti-cancer drugs, which are produced to US-FDA, ICH and EU standards at Indena's High Containment Manufacturing facilities in Settala, Italy. Indena's drug discovery strategy is to develop new chemical entities up to "Phase I/II" of clinical studies, and then license them to pharmaceutical companies.

Today Indena is also concentrating its efforts on the industrial production of high-quality standardised botanical derivatives, which are important ingredients in health food products. In fact, the company produces standardised extracts from edible plants that are traditionally recognised as having therapeutic properties, as well as from plants that have proven pharmacological value. Indena's research and production activities are particularly attentive to plant-based principles that have anti-oxidant properties and prevent damage caused by free radicals.

Backed by more than 90 years of botanical experience, Indena has developed a plantation network, managed by experts, to supply its research and production centres with officinal plants, while ensuring bio-diversity and protecting the ecosystem from uncontrolled harvesting. Today more than 60% of the raw material used in manufacturing comes from cultivations.

Indena's decades-long global presence in the plant extraction industry is a guarantee of its in-depth knowledge and understanding of the business, market trends and legal considerations. There is constant communication and interaction between the company's experts, who cooperate on the updating of all the main pharmacopoeias, and the major international regulatory authorities such as WHO, EMA, and ESCOP.
The company has more than 150 primary patents and has published more than 700 scientific studies.

Articles On Food Ingredients First
DSM Vitafoods Europe 2024


Vitafoods Europe 2024 live: dsm-firmenich unveils innovative microbiome-targeted vitamin B2 solution

16 May 2024 --- At the ongoing Vitafoods Europe trade show in Geneva, Switzerland, dsm-firmenich launches the “biotic” vitamin, Humiome B2, designed to ensure targeted vitamin B2... Read More

A cup of ice cream is placed on a table.


Beyond The Headlines: Unilever highlights ice cream sales drop, Tate & Lyle expand in soluble fibers

27 Oct 2023 --- In industry news this week, Indena and dsm-firmenich have joined forces to improve natural solutions, while Unilever reported a decline in ice cream sales and an uptick in... Read More


Indena Granted Certification for Main Production Sites in Italy and France

08 May 2017 --- Indena has been granted the OHSAS 18001:2007 certification for its production sites in Settala (Milan – Italy) and Tours, France. This certification guarantees that the... Read More


Indena’s Curcumin Phospholipid Gets GRAS Status

24 Feb 2016 --- Indena has received another important acknowledgement supporting the safety profile of its products. Its curcumin phospholipid (Meriva) obtained self-affirmed GRAS (Generally... Read More


Indena and YOUCARE at the Forum Économique Franco-Chinois

22 Apr 2014 --- Indena S.A.S. – part of the Indena group, the world’s leading producer of high quality plant-derived active principles for use in the pharmaceutical, health-food and personal care... Read More


New Ingredient Solution for Digestive Health

29 May 2017 --- Indena is bringing at Vitafoods 2017 Prodigest, its latest innovation for natural digestive relief. Prodigest is a patented combination of two standardized ingredients: a unique extract of artichoke leaves (Cynara cardunculus L.) and a similarly unique lipophilic CO2 extract of ginger roots (Zingiber officinale Rosc.). To develop Prodigest, Indena redesigned these two well-known extracts to create a product which is backed up by exhaustive clinical data supporting both its functionality (gastric emptying) and effectiveness (relief of discomforts). The inventive synergy of artichoke leaves and ginger extracts developed by Indena has been proven to be more effective than the two single extracts separately. Two recent human clinical studies with Prodigest have shown improved gastric motility symptoms related to digestive discomforts, known to cause gastric fullness, pain, bloating and nausea. 


New and Promising Botanical Ingredient

07 Jun 2015 --- Boswellic acids have long been considered the main bioactive components of Boswellia serrata, and many studies in vitro and in animals have confirmed their bioactivities. In particular, recent mechanistic studies have validated the capacity of the β-boswellic acids group to modulate inflammatory response, but preliminary pharmacokinetic studies in animals and humans have highlighted their poor oral absorption. To overcome this problem, Indena has formulated a purified mixture of boswellic acids from Boswellia serrata with lecithin, taking advantage of its proprietary Phytosome technology platform to optimize their absorption.