Hydrolyzed Collagen Product Shown to Improve Bone Status and Prevents Bone Loss
In response to consumer concerns about long-term bone health, for several years Rousselot has been carrying out studies to demonstrate that an oral intake of Peptan may have a positive impact in preserving Bone Mineral Density (BMD) before osteoporosis appears.
Oct 24 2011 --- The latest Rousselot study conducted at AgroParisTech, Nutrition Physiology and Ingestive Behavior laboratory under Pr. Daniel Tomé's supervision and published in September 2011 in Osteoporosis International has confirmed the benefits of Peptan on bone health.
Osteoporosis is a critical disorder characterized by bone loss and an increased risk of fracture. It results from an imbalance between bone formation and bone resorption occurring mainly, although not only, in post-menopausal women as a consequence of estrogen deficiency that in turn increases osteoclast activity.
In response to consumer concerns about long-term bone health, for several years Rousselot has been carrying out studies to demonstrate that an oral intake of Peptan may have a positive impact in preserving Bone Mineral Density (BMD) before osteoporosis appears.
The aim of the latest study was to evaluate the effect of Peptan hydrolyzed collagen on the bone health of ovariectomized mice (OVX) of different ages. Animals were divided into different groups: some groups of mice ingested Peptan after OVX; another group of mice ingested Peptan several weeks before OVX and continued over additional weeks; another ingested Raloxifene - a drug commonly indicated for osteoporosis - instead of hydrolyzed collagen.
Twenty-six weeks after the OVX procedure, Peptan hydrolyzed collagen ingestion was able to significantly improve BMD and some femur biomechanical parameters. Moreover, hydrolyzed collagen ingestion for one month before surgery prevented a BMD decrease. The third major finding was that Peptan hydrolyzed collagen could prevent a BMD decrease as efficiently as Raloxifene.
In conclusion, the study confirmed once more the importance of Peptan as a nutritional complement to prevent bone loss, and to restore bone mineral density.
